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"It is the anger…the anger ignites the Sith poison."
— Satal Keto

Sith Poison is a biological toxin, being a product of Sith alchemy, that when absorbed in sufficient quantity, multiplies the rage felt by a person. In action it is more of a disease, taking up residence in the victim's body and setting off chemical reactions that rapidly diminish the victim's ability to resist the pull of the Dark Side of the Force. The poison can be fatal unless counteracted by strong Jedi powers, and even then its effects are likely to remain.

Sith poison can either be ingested or administered by medical means, usually via syringe; both of these methods bring a much shorter reaction time upon the victim. It can even be directly applied through the mucuous membranes of an already exposed injury.

After being introduced to the body, the poison is absorbed on a molecular level, feeding on the individual's anger and drawing them closer to the Dark Side. The individual's judgment becomes less rational, and they eventually become so enraged that they begin to lash out involuntarily with the Dark Side.

Use of Sith poison tends to be extremely rare and implemented by only the most proficient Sith alchemists. While creating the infusion, the alchemist expends much of their own Dark Side energy; the process is laborous. Once the toxin is finished the alchemist then has a powerful weapon to use against any unsuspecting Jedi.

A more insidious version of Sith poison was developed by Uvon Okdoro of the Cult of Shadow and dubbed by the Master Alchemist as Shadow Poison.

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